Women who have higher levels of appetite control hormone leptin to reduce symptoms of depression, the apparent inverse relationship is not related to body mass index (BMI), a new study found. The study was presented Monday at the Endocrine Society 93rd Annual Meeting in Boston, USA.
"Animal data suggest that leptin may reduce anxiety, improve depression. Our study showed that in women, leptin may indeed have antidepressant qualities, said:" The study's lead author, Elizabeth Lawson, Massachusetts General Hospital and Harvard Medical School, Boston.
Leptin, the fat cells, signals satiety, or fullness of the product. This is a low-thin women and obese women with high, according to Lawson. She also said that a typical anxiety and depression in the low leptin levels increased incidence of certain conditions. These include eating disorders, anorexia nervosa, which is abnormally low body weight and body fat, functional hypothalamic amenorrhea, including women has been stopped, despite the weight of normal menstruation.
"It is unclear whether low leptin levels contribute to depression in these women's development," Lawson said.
She and her colleagues studied 64 women with leptin levels and anxiety and depression relationship. Fifth of women have anorexia nervosa, 12 were of normal weight hypothalamic amenorrhea, 20 normal weight and health, 17 were overweight or obese, but still healthy.
All subjects were asked questions to assess their symptoms that indicate that high scores of depression and anxiety symptoms. In addition to measuring blood levels of leptin, the researchers assessed the women's body mass index, height and weight measurements.
Leptin and the relationship between depressive symptoms independent of body mass index. This finding suggests that leptin may be involved in symptoms of depression, and this effect is not a function of low body weight, Lawson said.
"Further studies of human leptin administration to see whether the hormone in the treatment of depression in the potential role of very important," she said.
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