6/06/2011

Bisphenol A exposure to be underestimated, new research says

University of Missouri's new study suggests that dietary exposure through the controversial chemical bisphenol A (BPA) has been from the previous laboratory tests show that underestimated.
 
The findings, published in Monday Outlook in the environment and health.
 
In this study, the researchers compared the stability of these were given a dietary supplement for all-day bisphenol A bisphenol A concentration of mice, a single exposure of the more common laboratory method, found an increase in the blood of mice double phenol A absorption and accumulation.
 
Through continuous exposure in the feed, which is considered to be exposure to this chemical in the basic line of animals and humans to bisphenol A in mice. Previous research in the study of bisphenol A, mice exposed to BPA only through a one-time management.
 
Following the exposure through diet, in bisphenol A, the active form, is the biggest threat because it can bind to steroid hormone receptors, play a negative impact is absorbed and accumulated to form the animals were significantly greater increase.
 
"People are mainly exposed through and unconsciously, as a variety of plastic and used to store our food paper containers with bisphenol A diet formulated to bisphenol A," Rosenfeld said, and Cheryl, Associate Professor of Biomedical Sciences and the corresponding author. "We know that bisphenol A in the active form of steroid hormone receptor binding, which means it can affect the estrogen, thyroid and testicular hormone function. It may also cause genetic mutations. Therefore, this chemical can prevent us from reproductive capacity, and may cause abnormal behavior, we are just beginning to understand. "
 
Studies have shown that more than 80 billion pounds of bisphenol A production of each year, more than ninety percent of people in the United States of bisphenol A in the body and measurable amount.
 
"When bisphenol A is through the food has taken the form may remain active for a longer period of time, in the body than when it is handled through a single, it does not reflect the continuous exposure, occurs in animal and human requirements," said Rosenfeld. "We need further studies to determine which intake of bisphenol A, and subsequently released into the blood to become concentrated in the back distributed throughout the body."

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